Preliminary Phytochemical Profile and Antibacterial Evaluation of Viburnum grandiflorum Wall

Viburnum grandiflorum Wall. ex DC., is a plant of Himalaya and Hazara region of Pakistan which was screened for bioactive secondary metabolite and screen for biological activity. Preliminary phytochemical profiling indicated the presence of different classes of secondary plant metabolites such as alkaloids, terpenoids, saponins, anthraquinone. These secondary metabolites vary in types in different parts of the plant, which also depends on the type of the solvent extraction. Ethyl acetate and methanolic fraction containing alkaloids and flavonoids while steroids, terpenoids, anthraquinones and saponins were present in n-hexane, chloroform, ethyl acetate and methanolic fraction respectively. n-Hexane, chloroform, ethyl acetate and methanol extracts of V. grandiflorum were most active, showing activity against three selected bacterial strains and thus showed highest inhibitory zone (20 mm) at tested concentration (22 mg/ml) which could be attributed to the presence these phytochemicals.